Nicholas J White Selected Research

Artemisinins

1/2023	An artesunate pharmacometric model to explain therapeutic responses in falciparum malaria.
1/2019	Sequential Open-Label Study of the Safety, Tolerability, and Pharmacokinetic Interactions between Dihydroartemisinin-Piperaquine and Mefloquine in Healthy Thai Adults.
1/2017	The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread.
5/2016	Safety of artemisinins in first trimester of prospectively followed pregnancies: an observational study.
11/2013	Optimal sampling designs for estimation of Plasmodium falciparum clearance rates in patients treated with artemisinin derivatives.
3/2013	Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.
8/2011	Artemisinin resistance in Plasmodium falciparum is associated with an altered temporal pattern of transcription.
1/2007	Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand.
4/2004	Antimalarial drug resistance.

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Nicholas J White Research Topics

Disease

267	Malaria 05/2024 - 01/2002
192	Falciparum Malaria (Plasmodium falciparum Malaria) 05/2024 - 03/2002
86	Infections 02/2024 - 02/2002
56	Vivax Malaria 04/2024 - 05/2003
29	Glucosephosphate Dehydrogenase Deficiency 05/2024 - 12/2008
27	Hemolysis 05/2024 - 04/2005
19	COVID-19 04/2024 - 01/2020
18	Parasitemia 12/2020 - 03/2002
16	Fever (Fevers) 10/2021 - 02/2002
15	Body Weight (Weight, Body) 10/2021 - 04/2005
14	Melioidosis 01/2020 - 03/2003
13	Reinfection 01/2018 - 10/2004
10	Coma (Comas) 01/2019 - 07/2003
9	Human Influenza (Influenza) 01/2024 - 09/2006
8	Typhoid Fever (Typhoid) 01/2021 - 07/2002
8	Cryptococcal Meningitis 01/2021 - 09/2002
8	Acidosis 01/2019 - 08/2004
8	Sepsis (Septicemia) 01/2019 - 09/2003
8	Acute malaria 01/2015 - 05/2002
7	Cardiotoxicity 10/2022 - 01/2004
7	Cerebral Malaria 01/2017 - 11/2004
6	Leptospirosis 01/2020 - 11/2004
5	Vomiting 01/2023 - 12/2002
5	Hemorrhage 01/2023 - 02/2002
5	Anemia 12/2015 - 09/2005
4	Torsades de Pointes (Torsade de Pointes) 10/2022 - 01/2021
4	Hemolytic Anemia 06/2022 - 02/2014
4	Cardiac Arrhythmias (Arrythmia) 04/2021 - 11/2018
4	Bacterial Infections (Bacterial Infection) 01/2021 - 02/2005
4	Hypoxia (Hypoxemia) 03/2019 - 11/2009
4	Scrub Typhus (Typhus, Scrub) 07/2007 - 11/2004
4	Meningeal Tuberculosis (Tuberculous Meningitis) 03/2007 - 03/2004
3	Nausea 01/2023 - 12/2002
3	Dizziness (Lightheadedness) 01/2023 - 12/2002
3	Bradycardia 01/2023 - 01/2021
3	Jaundice (Icterus) 01/2022 - 11/2005
3	Parasitic Diseases (Parasitic Disease) 01/2021 - 01/2012
3	Birth Weight (Birth Weights) 01/2020 - 03/2002
3	Shock 01/2019 - 09/2003

Drug/Important Bio-Agent (IBA)

119	Antimalarials (Antimalarial Agents)IBA 03/2023 - 04/2002
107	artemisinin (artemisinine)IBA 05/2024 - 03/2002
94	ArtesunateIBA 01/2024 - 03/2002
64	Primaquine FDA Link 05/2024 - 07/2003
51	artenimol (dihydroartemisinin)IBA 05/2024 - 04/2002
50	piperaquineIBA 05/2024 - 01/2004
43	Chloroquine (Aralen)FDA LinkGeneric 10/2022 - 03/2002
34	Quinine (Quinson)FDA Link 01/2020 - 03/2002
30	Mefloquine (Lariam)FDA LinkGeneric 04/2024 - 03/2002
28	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2023 - 10/2004
24	Anti-Bacterial Agents (Antibiotics)IBA 10/2022 - 07/2002
21	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 01/2023 - 04/2010
15	Amodiaquine (Camoquin)FDA Link 01/2023 - 01/2004
13	pyrimethamine drug combination fanasil (Fansidar)FDA Link 01/2022 - 05/2003
12	Lactic Acid (Lactate)FDA LinkGeneric 03/2019 - 03/2002
11	Antiviral Agents (Antivirals)IBA 04/2024 - 03/2003
10	Lumefantrine FDA Link 04/2024 - 06/2006
10	EnzymesIBA 03/2018 - 02/2002
10	Artemether FDA Link 01/2018 - 12/2003
9	ArtemisininsIBA 01/2023 - 04/2004
9	Hydroxychloroquine (Plaquenil)FDA LinkGeneric 07/2021 - 01/2020
9	Proteins (Proteins, Gene)FDA Link 03/2016 - 04/2005
8	AntigensIBA 01/2022 - 03/2004
8	8-aminoquinolineIBA 01/2021 - 10/2011
7	AcidsIBA 01/2019 - 08/2004
6	tafenoquineIBA 02/2024 - 02/2017
6	Ivermectin (Mectizan)FDA Link 01/2023 - 01/2020
6	Azithromycin (Zithromax)FDA LinkGeneric 10/2022 - 01/2010
6	AntibodiesIBA 01/2022 - 07/2007
6	CytokinesIBA 01/2006 - 07/2002
5	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 06/2022 - 06/2005
5	VaccinesIBA 01/2022 - 11/2004
5	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 07/2012
5	Biomarkers (Surrogate Marker)IBA 01/2017 - 02/2011
5	TabletsIBA 01/2017 - 01/2003
5	Oseltamivir (Tamiflu)FDA Link 01/2016 - 09/2006
5	proguanil drug combination atovaquone (malarone)FDA Link 09/2014 - 12/2002
5	Thiamine (Aneurin)FDA Link 07/2014 - 09/2003
5	Indicators and Reagents (Reagents)IBA 04/2013 - 08/2004
4	hemozoinIBA 11/2022 - 02/2004
4	Dexamethasone (Maxidex)FDA LinkGeneric 07/2021 - 10/2004
4	quinolineIBA 01/2021 - 08/2007
4	Hemoglobins (Hemoglobin)IBA 01/2020 - 01/2017
4	Immunoglobulin G (IgG)IBA 01/2019 - 08/2004
4	CreatinineIBA 03/2018 - 08/2011
4	Doxycycline (Periostat)FDA LinkGeneric 07/2010 - 11/2004
4	ImmunosorbentsIBA 09/2005 - 02/2002
3	Transaminases (Aminotransferases)IBA 02/2024 - 07/2010
3	Oxidants (Oxidizing Agents)IBA 06/2022 - 01/2017
3	Ofloxacin (Ofloxacine)FDA LinkGeneric 01/2021 - 03/2005
3	Fluconazole (Zonal)FDA LinkGeneric 01/2021 - 07/2002
3	Amphotericin B (Amphotericin)FDA LinkGeneric 01/2021 - 05/2004
3	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA 01/2019 - 01/2002

Therapy/Procedure

70	Therapeutics 04/2024 - 07/2002
23	Mass Drug Administration 05/2024 - 01/2012
14	Aftercare (After-Treatment) 01/2019 - 07/2002
10	Chemoprevention 01/2023 - 03/2012
7	Insecticide-Treated Bednets 11/2018 - 09/2002
5	Prenatal Care (Care, Prenatal) 01/2023 - 11/2010
5	Resuscitation 01/2020 - 09/2005
4	Blood Transfusion (Blood Transfusions) 01/2021 - 11/2014